Children, coronavirus and Kawasaki disease…

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Excerpts:

by Frontiers

Children suffering from sickness and diarrhea, coupled with a fever or history of exposure to coronavirus, should be suspected of being infected with COVID-19, recommends a new study published in Frontiers in Pediatrics.

The research also suggests that the gastrointestinal symptoms first suffered by some children hints at potential infection through the digestive tract, as the type of receptors in cells in the lungs targeted by the virus can also be found in the intestines.

“Most children are only mildly affected by COVID-19 and the few severe cases often have underlying health issues. It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms or suffers from another illness,” says author of this study, Dr. Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital, Wuhan, China.

He continues, “Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus.”

In this study, Li and his colleagues detail the clinical features of children admitted to hospital with non-respiratory symptoms, which were subsequently diagnosed with pneumonia and COVID-19.

“These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma. All had pneumonia confirmed by chest CT scan before or soon after admission and then confirmed to have COVID-19. While their initial symptoms may have been unrelated, or their COVID-19 symptoms were initially mild or relatively hidden before their admission to hospital, importantly, 4 of the 5 cases had digestive tract symptoms as the first manifestation of this disease.”

By highlighting these cases, Li hopes that doctors will use this information to quickly diagnose and isolate patients with similar symptoms, which will aid early treatment and reduce transmission.

For more:

https://medicalxpress.com/news/2020-05-coronavirus-infection-childrenit.html

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Excerpts:

by Michael Hill

Two young children and a teenager have now died in New York state from a possible complication from the coronavirus involving swollen blood vessels and heart problems, Gov. Andrew Cuomo said Saturday.

At least 73 children in New York have been diagnosed with symptoms similar to Kawasaki disease—a rare inflammatory condition in children—and toxic shock syndrome. Most of them are toddlers and elementary-age children.

Cuomo announced two more deaths a day after discussing the death of a 5-year-old boy Thursday at a New York City hospital. A 7-year old in Westchester County and a teenager in Suffolk County on Long Island also died. There is no proof that the virus causes the mysterious syndrome.

Cuomo said children had tested positive for COVID-19 or the antibodies but did not show the common symptoms of the virus when they were hospitalized.

“This is the last thing that we need at this time, with all that is going on, with all the anxiety we have, now for parents to have to worry about whether or not their youngster was infected,” Cuomo said at his daily briefing.

New York is helping develop national criteria for identifying and responding to the syndrome at the request of the Centers for Disease Control, Cuomo said.

Children elsewhere in the U.S. have also been hospitalized with the condition, which was also seen in Europe.

Doctors still believe that most children with COVID-19 develop only mild illness.

At least 3,000 U.S. children are diagnosed with Kawasaki disease each year. It is most common in children younger than 6 and in boys.

Symptoms include prolonged fever, severe abdominal pain and trouble breathing.


https://medicalxpress.com/news/2020-05-ny-children-die-syndrome-possibly.html

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Excerpts:

Cuomo told a daily briefing that he was increasingly worried about a syndrome that shares symptoms with toxic shock and Kawasaki disease, which he said included inflammation of the blood vessels and potentially fatal damage to the heart.

He said three children – including a five-year old disclosed on Friday – have died from such symptoms while also testing positive for COVID-19 or related antibodies, suggesting a link that was still not fully understood.

Cuomo, who has emerged as a leading national voice on states’ response to the coronavirus crisis, said state health officials were reviewing 73 similar cases, which have rattled a prior assumption that children were largely not susceptible to the novel coronavirus.

“We are not so sure that is the fact anymore. Toddler, elementary school children are presenting symptoms similar to Kawasaki disease or toxic shock-like syndrome,” Cuomo said. “It’s very possible that this has been going on for several weeks and it hasn’t been diagnosed as related to COVID.”

The syndrome shares symptoms with toxic shock and Kawasaki disease, which is associated with fever, skin rashes, swelling of the glands, and in severe cases, inflammation of arteries of the heart. Scientists are still trying to determine whether the syndrome is linked with the new coronavirus because not all children with it have tested positive for the virus.

https://www.reuters.com/article/us-health-coronavirus-usa-ny/rare-syndrome-tied-to-covid-19-kills-three-children-in-new-york-cuomo-says-idUSKBN22L0OF



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