..
So far, Denmark has not seen a worst-case scenario for the COVID-19 spread. Per The Washington Post, the highly vaccinated Denmark has seen stabilized COVID-19 case numbers after a brief surge tied to the omicron variant. The country’s success — which is measured as avoiding a massive surge — may be a sign at how highly vaccinated countries could deal with the omicron variant.
..
This is disinformation:
..
DENMARK: 90% OF OMICRON INFECTIONS FOUND IN “FULLY VACCINATED AND BOOSTERED INDIVIDUALS”
too many shots might cause a sort of IMMUNE SYSTEM FATIGUE, compromising the body’s ability to fight the coronavirus.”
DENMARK TO STOP GIVING BOOSTER INJECTIONS
..
This is the true situation:
..
..
..
If Your Time is short
- A Danish study shows a sharp drop in vaccine effectiveness over time against the omicron variant of COVID-19 in people with two doses of the Pfizer or Moderna vaccine.
- But it also shows protection is quickly restored with a Pfizer booster dose. There was not enough data about a Moderna booster.
- The study’s authors said that their findings prove a need to ramp up vaccination and booster doses to fight the variant.
.
The authors wrote that the study showed vaccine effectiveness against both variants after two doses, though they were each more effective against delta. It also found that the vaccine effectiveness declined rapidly against both variants after several months, but that it was restored after a Pfizer booster dose.
“In light of the exponential rise in Omicron cases, these findings highlight the need for massive rollout of vaccinations and booster vaccinations,” they wrote.
.
The Rogue Review story pointed to the two negative numbers, and said these figures show that those vaccinated with Pfizer are 76.5% more likely to get omicron than the unvaccinated, and that Moderna vaccine recipients are 39.3% more likely to get omicron than the unvaccinated. That’s not what the study concluded.
In the discussion section of the study, the authors explained that the negative numbers suggest that different behavior “and/or exposure patterns in the vaccinated and unvaccinated” caused underestimation of the vaccines’ effectiveness.
“This was likely the result of omicron spreading rapidly initially through single (super-spreading) events causing many infections among young, vaccinated individuals,” they wrote.
Blicher Schelde said there are several reasons why the number might be negative. First, vaccinated people may test more than unvaccinated people, she said.
Also, the data is from the first generations of omicron cases in Denmark, which occurred disproportionately among those who were traveling internationally and people in their social and professional circles who were largely vaccinated, she said. Therefore, there was likely an overrepresentation of vaccinated people.
Finally, discrepancies in risk behavior between vaccinated and unvaccinated people will lead to an underestimate of vaccine effectiveness, she wrote, pointing out that the “increasingly small cohort of unvaccinated people” in Denmark may take extra precautions because they are not vaccinated.
.
The study shows a sharp decline in vaccine effectiveness against omicron over time in people who have received two doses. It also shows that effectiveness is restored with a booster dose of Pfizer, although there is not enough data on a Moderna booster. The authors said the study did not conclude that vaccinated people are more likely to be infected with omicron than people who are not vaccinated.
They said their findings prove the need for more vaccinations and booster doses to combat the rapid rise of omicron.
We rate this claim False.
..
..
Excerpts:
SARS-CoV-2 Omicron VOC Transmission in Danish Households
View ORCID ProfileFrederik Plesner Lyngse, View ORCID ProfileLaust Hvas Mortensen, View ORCID ProfileMatthew J. Denwood, View ORCID ProfileLasse Engbo Christiansen, View ORCID ProfileCamilla Holten Møller, View ORCID ProfileRobert Leo Skov, View ORCID ProfileKatja Spiess, View ORCID ProfileAnders Fomsgaard, Maria Magdalena Lassaunière, View ORCID ProfileMorten Rasmussen, View ORCID ProfileMarc Stegger, Claus Nielsen, View ORCID ProfileRaphael Niklaus Sieber, View ORCID ProfileArieh Sierra Cohen, Frederik Trier Møller, View ORCID ProfileMaria Overvad, View ORCID ProfileKåre Mølbak, View ORCID ProfileTyra Grove Krause, View ORCID ProfileCarsten Thure Kirkeby doi: https://doi.org/10.1101/2021.12.27.21268278 This article is a preprint and has not been peer-reviewed [what does this mean?]. It reports new medical research that has yet to be evaluated and so should not be used to guide clinical practice.
1 Abstract
The Omicron variant of concern (VOC) is a rapidly spreading variant of SARS-CoV-2 that is likely to overtake the previously dominant Delta VOC in many countries by the end of 2021.
We estimated the transmission dynamics following the spread of Omicron VOC within Danish households during December 2021. We used data from Danish registers to estimate the household secondary attack rate (SAR).
Among 11,937 households (2,225 with the Omicron VOC), we identified 6,397 secondary infections during a 1-7 day follow-up period. The SAR was 31% and 21% in households with the Omicron and Delta VOC, respectively. We found an increased transmission for unvaccinated individuals, and a reduced transmission for booster-vaccinated individuals, compared to fully vaccinated individuals. Comparing households infected with the Omicron to Delta VOC, we found an 1.17 (95%-CI: 0.99-1.38) times higher SAR for unvaccinated, 2.61 times (95%-CI: 2.34-2.90) higher for fully vaccinated and 3.66 (95%-CI: 2.65-5.05) times higher for booster-vaccinated individuals, demonstrating strong evidence of immune evasiveness of the Omicron VOC.
Our findings confirm that the rapid spread of the Omicron VOC primarily can be ascribed to the immune evasiveness rather than an inherent increase in the basic transmissibility.
.
4 Results
A total of 2,225 primary cases with the Omicron VOC and 9,712 primary cases with the Delta VOC were included (Table 1). The SAR was 31% in households with the Omicron VOC and 21% in households with the Delta VOC. Generally, the estimated SAR was higher for the Omicron VOC than for the Delta VOC, for all age groups. Unvaccinated potential secondary cases experienced similar attack rates in households with the Omicron VOC and the Delta VOC (29% and 28%, respectively), while fully vaccinated individuals experienced secondary attack rates of 32% in household with the Omicron VOC and 19% in households with the Delta VOC. For booster-vaccinated individuals, Omicron was associated with a SAR of 25%, while the corresponding estimate for Delta was only 11%.
.
5 Discussion and Conclusion
Our results show that the Omicron VOC is generally 2.7-3.7 times more infectious than the Delta VOC among vaccinated individuals (Table 3). This observation is in line with data from (18), which estimated that 19% of Omicron VOC primary cases in households in the UK resulted in at least one other infection within the household, compared to only 8.3% of those associated with the Delta VOC. Furthermore, we show that fully vaccinated and booster-vaccinated individuals are generally less susceptible to infection compared to unvaccinated individuals (Table 2). We also show that booster-vaccinated individuals generally had a reduced transmissibility (OR: 0.72, CI: 0.56-0.92), and that unvaccinated individuals had a higher transmissibility (OR: 1.41, CI: 1.27-1.57), compared to fully vaccinated individuals.
.
To conclude, we found an increased susceptibility for unvaccinated individuals, and a reduced susceptibility for booster-vaccinated individuals, compared to fully vaccinated individuals in households infected with the Delta VOC. Additionally, we found a reduced susceptibility for booster-vaccinated individuals in households infected with the Omicron VOC. Furthermore, we found an increased transmissibility from unvaccinated individuals, and a reduced transmissibility from booster-vaccinated individuals, compared to fully vaccinated individuals. Lastly, we we found a general higher transmission in households infected with the Omicron VOC relative to the Delta for both unvaccinated, fully vaccinated and booster-vaccinated individuals. The Omicron VOC showed immune evasiveness for fully vaccinated and booster-vaccinated individuals. Our results confirm that booster vaccination has the potential to reduce Omicron VOC transmission in households, although vaccination as a strategy for epidemic control is increasingly challenged by the immune evasiveness of the Omicron VOC.
Comparing Omicron VOC to Delta VOC, we found an 1.17 (95%-CI: 0.99-1.38) times higher SAR for unvaccinated, 2.61 times (95%-CI: 2.34-2.90) higher for fully vaccinated and 3.66 (95%-CI: 2.65-5.05) times higher for booster-vaccinated individuals, demonstrating strong evidence of immune evasiveness of the Omicron VOC.
https://www.medrxiv.org/content/10.1101/2021.12.27.21268278v1.full-text
..
How the third COVID-19 booster shot can slow the omicron variant
A new study suggests the third COVID-19 vaccine shot can slow the spread of the omicron variant
By Herb Scribner@HerbScribner Dec 29, 2021, 5:00pm MST
A new study suggests that the third COVID-19 vaccine shot — the COVID-19 booster shot — can slow the spread of the omicron variant.
- The study was done by the University of Copenhagen, Statistics Denmark and Statens Serum Institut.
The study, which was published on medRxiv and was not peer-reviewed, looked at about 12,000 households in Denmark to see how fast the omicron variant could spread.
- The data showed that there was a reduced transmission of the omicron variant for those who got the third COVID-19 vaccine shot, otherwise known as the booster shot.
So far, Denmark has not seen a worst-case scenario for the COVID-19 spread. Per The Washington Post, the highly vaccinated Denmark has seen stabilized COVID-19 case numbers after a brief surge tied to the omicron variant. The country’s success — which is measured as avoiding a massive surge — may be a sign at how highly vaccinated countries could deal with the omicron variant.
..
weehingthong 