Vaccines may be revamped to avoid blood clots, German scientists claim in findings published in a pre-print journal paper…




Cause of blood clots linked to AstraZeneca and J&J Covid vaccines ‘SOLVED’ and scientists claim they know how to fix it

  • 20:58, 26 May 2021
  • Updated: 0:15, 27 May 2021

BOFFINS claim to have cracked the cause of rare blood clots linked to Covid jabs and say they know how to solve it.

They say the phenomenon is caused by “floating mutant proteins” which can occur when a vaccine sends the spike protein of the Sars-Cov-2 virus into the wrong part of a cell.

Lead scientist Rolf Marschalek said US drugs firm Johnson & Johnson has already been in touch to ask about his team’s research at the Goethe University in Frankfurt.

But he said he had not yet discussed its findings with AstraZeneca, manufacturer of the Oxford vaccine.

He said: “They never contacted us so we never spoke to them, but if they do I can tell them what to do to make a better vaccine.”

Prof Marschalek believes the cause is “floating mutant proteins,” the Financial Times reports.

He said the issue lies with the adenovirus vectors – which both the J&J and AstraZeneca vaccines use to send the spike protein of the Sars-Cov-2 virus into the body.

The German researcher and other scientists said this method sends the spike protein into the cell nucleus rather than the cytosol fluid inside the cell.

Once inside the cell nucleus, certain parts of the spike protein split apart and create mutant versions.

They are then unable to bind to the cell membrane and floating mutant proteins are instead secreted by cells into the body.

According to Marschalek’s theory, this can trigger blood clots in roughly one in 100,000 people.

But Marschalek believes there is a straight forward “way out” if the vaccine developers can modify the sequence of the spike protein to prevent it splitting apart. 

“With the data we have in our hands we can tell the companies how to mutate these sequences, coding for the spike protein in a way that prevents unintended splice reactions,” he said.

Meanwhile, some scientists have said more evidence is needed to substantiate the latest claims.

“There is evidence missing to show the causal chain from the splice . . . of the spike protein to the thrombosis events,” Johannes Oldenburg, professor of transfusion medicine at the university of Bonn, said.

“This is still a hypothesis that needs to be proven by experimental data.”

Marschalek said he had presented his lab’s findings to the German government’s Paul-Ehrlich Institute and to the country’s advisory body on vaccination and immunisation.


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