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The New England Journal of Medicine (http://NEJM.org) is the world’s leading medical journal and website.
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This @NEJM paper did long-term follow-up on 3958 #pregnant ppl who received a #COVID19 #vaccine.
— Viki Male (@VikiLovesFACS) May 12, 2021
👉🏻 No increased risk of pregnancy-specific adverse events (including #miscarriage).
So why are ppl claiming it shows a 24x increased risk of miscarriage? 🧵
10.1056/NEJMoa2104983
The normal range quoted in the paper, based on these references, is 10 – 26%.
— Viki Male (@VikiLovesFACS) May 12, 2021
The range is large because lots of things affect miscarriage rate, so it varies a lot between studies.
But note the rate in the vaccinated population is within this normal range. 3/ pic.twitter.com/kXYxRTSUqS
Some people might be surprised that the miscarriage rate is as high as that. We perhaps have an artificially low view of how common miscarriage is because we tend not to talk about it.
— Viki Male (@VikiLovesFACS) May 12, 2021
But that’s a conversation for another time. Back to the paper… 5/
So where does this claim of a 24-fold increase in miscarriages come from? 7/ pic.twitter.com/3Wt8riPZ7A
— Viki Male (@VikiLovesFACS) May 12, 2021
The paper is actually about *stillbirths* (fetal loss after 20 weeks), rather than miscarriage, which occurs before 20 weeks. 9/ pic.twitter.com/RHC2066Y63
— Viki Male (@VikiLovesFACS) May 12, 2021
If we compare miscarriages in the vaccinated population with miscarriages in the general (unvaccinated) population, the rates are the same.
— Viki Male (@VikiLovesFACS) May 12, 2021
That is to say, there is no increased risk of #miscarriage associated with #COVID19 #vaccination. 11/
PS. I managed to give the DOI for the NEJM paper we are discussing, rather than the link. Oops! Here’s the link…https://t.co/h5GCZiuSMf
— Viki Male (@VikiLovesFACS) May 12, 2021
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weehingthong 